Papers
Here are my papers on various evolutionary biology things
L. Hagen. T. E. Keller , S. Neely, N. DePaula, C. Cooperman. Crisis Communications in the
Age of Social Media: A Network Analysis of Zika-Related Tweets. In Press, Social Science Computer Review .
I. Mendizabal, J. Zeng, T. E. Keller , S. V. Yi. Body-hypomethylated human genes harbor extensive intragenic transcriptional activity and are prone to cancer-associated dysregulation. In Press, Nucl. Acids. Res. , doi 10.1093/nar/gkx020 .
I. Mendizabal, L. Shi, T. E. Keller , G. Konopka, T. M. Preuss, T. Tsieh, E. Hu, Z. Zhang, B. Su, S. V. Yi. Comparative methylome analyses reveal epigenetic loci implicated in transcription regulation of human brains. In press, Molecular Biology and Evolution , doi 10.1093/molbev/msw176
T. E. Keller , J. E. Lasky, S. V. Yi. The multivariate association between genome-wide DNA methylation and climate across the range of Arabidopsis thaliana . pdf Molecular Ecology 25:1823–1837, 2016.
T. E. Keller , P. Han, S. V. Yi. Evolutionary transition of promoter and gene body DNA methylation across invertebrate-vertebrate boundary. Molecular Biology and Evolution 33:1019–1028, 2016.
I. Mendizabal, T. E. Keller , J. Zeng, S. V. Yi. Epigenetics and evolution . Integrative and Comparative Biology 54:31–42, 2014.
T.E. Keller , S. V. Yi. DNA methylation and evolution of duplicate genes . Proceedings of the National Academy of Sciences 111:5932–5937, 2014.
T.E. Keller , C. O. Wilke, J. J. Bull. Interactions between evolutionary processes at high mutation rates. pdf Evolution 66:2303–2314, 2012.
T.E. Keller , S. D. Mis, K. E. Jia , C. O. Wilke. Reduced mRNA secondary-structure stability near the start codon indicates functional genes in prokaryotes. Genome Biology and Evolution 4:80–88, 2012.
E. B. O’Dea, T.E. Keller , C. O. Wilke. Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations? PLoS Computational Biology 6:e1000811, 2010.
R. Springman, T. Keller , I. Molineux, J. J. Bull. Evolution at a high imposed mutation rate: adaptation obscures the load in Phage T7. Genetics 184:221–232 , 2010.
M. P. Salomon, D. Ostrow, N. Phillips, D. Blanton, W. Bour, T.E. Keller , L. Levy, T. Sylvestre, A. Upadhyay, C. F. Baer. Comparing mutational and standing genetic variability for fitness and size in Caenorhabditis briggsae and C. elegans . Genetics 183:685–92, 2009.
T.E. Keller , I. J. Molineux, J. J. Bull. Viral resistance evolution fully escapes a rationally designed lethal inhibitor. Molecular Biology and Evolution 26:2041–46, 2009.
D. Ostrow, N. Phillips, A. Avalos, D. Blanton, A. Boggs, T. Keller , L. Levy, J. Rosenbloom, C. F. Baer. Mutational bias for body size in rhabditid nematodes. Genetics 176:1653–61, 2007.
C. F. Baer, N. Phillips, D. Ostrow, A. Avalos, D. Blanton, A. Boggs, T. Keller , L. Levy, E. Mezerhane. Cumulative effects of spontaneous mutations for fitness in Caenorhabditis : role of genotype, environment and stress.
Genetics 174:1387–95, 2006.